Singh, C., Byungchang, J., Shrestha, N., Markhard, A., Panda, A., Calvo, S., Deik, A., Pan, X., Zuckerman, A., ben Saad, A., Corey, K., Sjoquist, J., Osganian, S., AminiTabrizi, R., Rhee, E., Shah, H., Goldberger, O., Mullen, A., Cracan, V., … Goodman, R. P. (2024). ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits. Cell Metabolism, 36, 1–15.

Pan, X., Heacock, M. L., Abdulaziz, E. N., Violante, S., Zuckerman, A. L., Shrestha, N., Yao, C., Goodman, R. P., Cross, J. R., & Cracan, V. (2023). A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells. Nature Chemical Biology.

Skinner, O. S., Blanco-Fernández, J., Goodman, R. P., Kawakami, A., Shen, H., Kemény, L. v., Joesch-Cohen, L., Rees, M. G., Roth, J. A., Fisher, D. E., Mootha, V. K., & Jourdain, A. A. (2023). Salvage of ribose from uridine or RNA supports glycolysis in nutrient-limited conditions. Nature Metabolism, 5(5), 765–776.

Fomin, V., Marshall, C., Tsai, S., Goodman, R., Schaefer, E., & Luther, J. (2022). Creation of an Inpatient Alcohol Liver Service Improves Early Liver Disease Detection in Patients With Alcohol Use Disorder. Clinical Gastroenterology and Hepatology, 3–5.

Vannier, A. G. L., Shay, J. E. S., Fomin, V., Patel, S. J., Schaefer, E., Goodman, R. P., & Luther, J. (2022). Incidence and Progression of Alcohol-Associated Liver Disease after Medical Therapy for Alcohol Use Disorder. JAMA Network Open, 5(5), E2213014.

Luther, J., Vannier, A. G. L., Schaefer, E. A. & Goodman, R. P. The circulating proteomic signature of alcohol-associated liver disease. JCI Insight 7, (2022).

Rath, S., Sharma, R., Gupta, R., Ast, T., Chan, C., Durham, T. J., Goodman, R. P., Grabarek, Z., Haas, M. E., Hung, W. H. W., Joshi, P. R., Jourdain, A. A., Kim, S. H., Kotrys, A. V., Lam, S. S., McCoy, J. G., Meisel, J. D., Miranda, M., Panda, A., Patgiri, A., Rogers, R., Sadre, S., Shah, H., Skinner, O. S., To, T. L., Walker, M. A., Wang, H., Ward, P. S., Wengrod, J., Yuan, C. C., Calvo, S. E., and Mootha, V. K. (2021) MitoCarta3.0: An updated mitochondrial proteome now with sub-organelle localization and pathway annotations. Nucleic Acids Res. 49, D1541–D1547. Pubmed

Goodman, R. P., Markhard, A. L., Shah, H., Sharma, R., Skinner, O. S., Clish, C. B., Deik, A., Patgiri, A., Hsu, Y.-H. H., Masia, R., Noh, H. L., Suk, S., Goldberger, O., Hirschhorn, J. N., Yellen, G., Kim, J. K., and Mootha, V. K. (2020) Hepatic NADH reductive stress underlies common variation in metabolic traits. Nature. 10.1038/s41586-020-2337-2. Pubmed

Related commentary: “Letting of electrons to cope with metabolic stress”

Luther, J., Khan, S., Gala, M. K., Kedrin, D., Sridharan, G., Goodman, R. P., Garber, J. J., Masia, R., Diagacomo, E., Adams, D., King, K. R., Piaker, S., Reinecker, H.-C., Yarmush, M. L., Argemi, J., Bataller, R., Dienstag, J. L., Chung, R. T., and Patel, S. J. (2020) Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation. Proc. Natl. Acad. Sci. 117, 201911870. Pubmed

Patgiri, A., Skinner, O. S., Miyazaki, Y., Schleifer, G., Marutani, E., Shah, H., Sharma, R., Goodman, R. P., To, T. L., Robert Bao, X., Ichinose, F., Zapol, W. M., and Mootha, V. K. (2020) An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance. Nat. Biotechnol. 38, 309–313. Pubmed

Goodman, R. P., Calvo, S. E., and Mootha, V. K. (2018) Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism. J. Biol. Chem. 293, 7508–7516. Pubmed