Luther, J., Vannier, A. G. L., Schaefer, E. A. & Goodman, R. P. The circulating proteomic signature of alcohol-associated liver disease. JCI Insight 7, (2022).

Goodman, R. P., Markhard, A. L., Shah, H., Sharma, R., Skinner, O. S., Clish, C. B., Deik, A., Patgiri, A., Hsu, Y.-H. H., Masia, R., Noh, H. L., Suk, S., Goldberger, O., Hirschhorn, J. N., Yellen, G., Kim, J. K., and Mootha, V. K. (2020) Hepatic NADH reductive stress underlies common variation in metabolic traits. Nature. 10.1038/s41586-020-2337-2. Pubmed

Related commentary: “Letting of electrons to cope with metabolic stress”

Rath, S., Sharma, R., Gupta, R., Ast, T., Chan, C., Durham, T. J., Goodman, R. P., Grabarek, Z., Haas, M. E., Hung, W. H. W., Joshi, P. R., Jourdain, A. A., Kim, S. H., Kotrys, A. V., Lam, S. S., McCoy, J. G., Meisel, J. D., Miranda, M., Panda, A., Patgiri, A., Rogers, R., Sadre, S., Shah, H., Skinner, O. S., To, T. L., Walker, M. A., Wang, H., Ward, P. S., Wengrod, J., Yuan, C. C., Calvo, S. E., and Mootha, V. K. (2021) MitoCarta3.0: An updated mitochondrial proteome now with sub-organelle localization and pathway annotations. Nucleic Acids Res. 49, D1541–D1547. Pubmed

Luther, J., Khan, S., Gala, M. K., Kedrin, D., Sridharan, G., Goodman, R. P., Garber, J. J., Masia, R., Diagacomo, E., Adams, D., King, K. R., Piaker, S., Reinecker, H.-C., Yarmush, M. L., Argemi, J., Bataller, R., Dienstag, J. L., Chung, R. T., and Patel, S. J. (2020) Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation. Proc. Natl. Acad. Sci. 117, 201911870. Pubmed

Patgiri, A., Skinner, O. S., Miyazaki, Y., Schleifer, G., Marutani, E., Shah, H., Sharma, R., Goodman, R. P., To, T. L., Robert Bao, X., Ichinose, F., Zapol, W. M., and Mootha, V. K. (2020) An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance. Nat. Biotechnol. 38, 309–313. Pubmed

Goodman, R. P., Calvo, S. E., and Mootha, V. K. (2018) Spatiotemporal compartmentalization of hepatic NADH and NADPH metabolism. J. Biol. Chem. 293, 7508–7516. Pubmed